Paper in Development about the loss of mesendodermal competence
We celebrated with cake and champagne the new paper from our lab published in Development.
The study, led by our former postdoc Pavel, determines the time during zebrafish development when the prospective ectoderm becomes unable to respond to mesendoderm-inducing Nodal signals. By activating the Nodal pathway with several different strategies, we showed that reduced expression of the Nodal coreceptor Oep causes loss of mesendodermal competence.
The champagne bottle was nicely decorated by Sabrina with the in situ hybridization protocol that was used in the paper.